Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep759 | Pituitary and Neuroendocrinology | ECE2022

About two cases of adipsic hypernatremia in adults, one with proven blood antibodies against subfornical organ (SFOAb).

Charfi Lilia , Dupuis Hippolyte , Lucile Szuwarski , Christine Gillot , Akari Utsunomiya , Vantyghem Marie-Christine

Adipsic hypernatremia, a rare hypothalamic disorder characterized by a loss of thirst in response to hypernatremia is more often reported in children. An autoimmune mechanism has been recently demonstrated. We report two cases.Case1: A lean 67-year-old female, with a history of multilocular sclerosis, was admitted, for severe hypernatremia (162 mmol/l) with low ADH level (0.5 pmol/l; N: 0.5-2). She did not complain of thirst, despite ideomotor slowing an...